BDBM676698 US20240166645, Compound I-22

SMILES C[C@@H](Nc1nc(C)nc2cc(=O)n(cc12)C1(C)CC1)c1cccc(c1)S(F)(F)(F)(F)F

InChI Key InChIKey=UIQJXRVXROPDRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676698   

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Wuhan Humanwell Innovative Drug

US Patent
LigandPNGBDBM676698(US20240166645, Compound I-22)
Affinity DataIC50: 21.7nMAssay Description:Table 1: The compound to be tested was prepared into a 10 mM stock solution with DMSO, and the compound was serially diluted using 1× test buffer. 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent