BDBM676579 US20240166643, Example 33

SMILES CC(C)(NC(=O)C1CN(C1)c1nc(ncc1Cl)N1CCNCC1)c1cnc2ccccn12

InChI Key InChIKey=VRTIXZMKCHNGGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676579   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM676579(US20240166643, Example 33)
Affinity DataIC50: 0.00400nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGlycylpeptide N-tetradecanoyltransferase(malaria parasite P. vivax)
Imperial College Innovations

US Patent
LigandPNGBDBM676579(US20240166643, Example 33)
Affinity DataIC50: 0.00700nMAssay Description:The IC50 values of certain Example Compounds of the invention, and for Comparative Examples 1 and 2, for Human NMT1 (HsNMT1) and Plasmodium vivax (Pv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent