BDBM676528 US20240166642, Example 16b

SMILES FC(F)(F)[C@H]1CCN[C@H](C1)c1ncccc1Cn1c2cc[nH]c2c(=O)[nH]c1=S

InChI Key InChIKey=PJAZPXMQVYRPNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676528   

TargetMyeloperoxidase(Human)
Astrazeneca

US Patent
LigandPNGBDBM676528(US20240166642, Example 16b)
Affinity DataIC50: 3.90nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetThyroid peroxidase(Human)
Astrazeneca

US Patent
LigandPNGBDBM676528(US20240166642, Example 16b)
Affinity DataIC50: 780nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent