BDBM675193 US20240158408, Compound YL109-P1
SMILES Fc1cc(cc(c1)C(F)(F)F)C(=O)Nc1cc(c2CCN3c2c1[C@H](NC3=O)c1cc(Cl)ccc1Cl)-c1ccc2ncnn2c1C#N
InChI Key InChIKey=QUUKORNGQPINPQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 675193
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [H1047R](Human)
280 Bio
US Patent
280 Bio
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:The ADP-Glo Kinase Assay Kit was used for the experiments. The following buffer solutions were prepared: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
280 Bio
US Patent
280 Bio
US Patent
Affinity DataIC50: 200nMAssay Description:The ADP-Glo Kinase Assay Kit was used for the experiments. The following buffer solutions were prepared: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, ...More data for this Ligand-Target Pair