BDBM675089 US20240158408, Compound YL012
SMILES Fc1ccc(Cl)c(c1)C1NC(=O)N2CCc3c2c1c(NC(=O)c1cc(F)cc(c1)C(F)(F)F)cc3N1CC(F)(F)C1
InChI Key InChIKey=LOMMHTRGSAKXFA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 675089
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [H1047R](Human)
280 Bio
US Patent
280 Bio
US Patent
Affinity DataIC50: 250nMAssay Description:The ADP-Glo Kinase Assay Kit was used for the experiments. The following buffer solutions were prepared: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
280 Bio
US Patent
280 Bio
US Patent
Affinity DataIC50: 5.13E+3nMAssay Description:The ADP-Glo Kinase Assay Kit was used for the experiments. The following buffer solutions were prepared: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, ...More data for this Ligand-Target Pair