BDBM674530 ((1R,4R,7R)-7-amino-2-azabicyclo[2.2.1]heptan-2-yl)(2-(3-(azetidin-3-ylmethyl)-4-(cyclopropylmethyl)-4H-thieno[3,2-b]pyrrol-5-yl)-7-methoxy-1l-methyl-1H-benzo[d]imidazol-5-yl)methanone and (2-(3-(3-amino-2-(chloromethyl)propyl)-4-(cyclopropylmethyl)-4H-thieno[3,2-b]pyrrol-5-yl)-7-methoxy-1l-methyl-1H-benzo[d]imidazol-5-yl)((1R,4R,7R)-7-amino-2-azabicyclo[2.2.1]heptan-2-yl)methanone::US11981680, Example 18

SMILES COc1cc(cc2nc(-c3cc4scc(CC5CNC5)c4n3CC3CC3)n(C)c12)C(=O)N1C[C@H]2CC[C@@H]1[C@@H]2N

InChI Key InChIKey=WUMXZMJDSNUNQV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674530   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM674530(((1R,4R,7R)-7-amino-2-azabicyclo[2.2.1]heptan-2-yl...)
Affinity DataIC50: 165nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
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Date in BDB:
8/13/2024
Entry Details
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