BDBM674522 US11981680, Example 10::cis/trans-((1R,4R,7R)-7-amino-2- azabicyclo[2.2.1]heptan-2-yl)(2-(4- (cyclopropylmethyl)-3-(4- hydroxycyclohexyl)-4H- thieno[3,2-b]pyrrol-5-yl)-7- methoxy-1-methyl-1H- benzo[d]imidazol-5-yl)methanone

SMILES COc1cc(cc2nc(-c3cc4scc(C5CCC(O)CC5)c4n3CC3CC3)n(C)c12)C(=O)N1C[C@H]2CC[C@@H]1[C@@H]2N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674522   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM674522(cis/trans-((1R,4R,7R)-7-amino-2- azabicyclo[2.2.1]...)
Affinity DataIC50: 46nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
Go to US Patent