BDBM674218 N-({(1r,4r)-4-[6- (5,6-dihydro- 4H-pyrrolo[1,2-b] pyrazol-3-yl)-2H- indazol-2-yl] cyclohexyl}methyl)- 3,5-difluoro-4- hydroxybenzamide::US20240150334, Example 48

SMILES Oc1c(F)cc(cc1F)C(=O)NC[C@H]1CC[C@@H](CC1)n1cc2ccc(cc2n1)-c1cnn2CCCc12

InChI Key InChIKey=JEXKLQAFKJFAAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674218   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674218(N-({(1r,4r)-4-[6- (5,6-dihydro- 4H-pyrrolo[1,2-b] ...)
Affinity DataIC50: 3.80nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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