BDBM674210 3,5-difluoro-4- hydroxy-N- {[(1r,4r)-4-{6-[1- (propan-2-yl)-1H- pyrazol-4-yl]-2H- indazol-2-yl} cyclohexyl]methyl} benzamide::US20240150334, Example 40

SMILES CC(C)n1cc(cn1)-c1ccc2cn(nc2c1)[C@H]1CC[C@H](CNC(=O)c2cc(F)c(O)c(F)c2)CC1

InChI Key InChIKey=HVJPAIVFWOSZAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674210   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674210(3,5-difluoro-4- hydroxy-N- {[(1r,4r)-4-{6-[1- (pro...)
Affinity DataIC50: 3.20nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent