BDBM672870 (S)-3-(4-(7-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)phenyl)-2-(2,6-dichloro-4-morpholinylbenzoylamino)methyl propionate::US20240150287, Example 39

SMILES COC(=O)[C@H](Cc1ccc(cc1)-n1c2c(Cl)cccc2n(C)c1=O)NC(=O)c1c(Cl)cc(cc1Cl)N1CCOCC1

InChI Key InChIKey=CLIAPLIXUZATPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 672870   

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672870(US20240150287, Example 39 | (S)-3-(4-(7-chloro-3-m...)
Affinity DataIC50: 3.65nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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