BDBM672851 (2S)-2-(4-(2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-2,6-dichlorobenzamido)-3-(4-(7′-chloro-2′-oxospiro[cyclopropane-1,3′-indoline]-1′-yl)phenyl)methyl propionate::US20240150287, Example 20

SMILES COC(=O)[C@H](Cc1ccc(cc1)N1C(=O)C2(CC2)c2cccc(Cl)c12)NC(=O)c1c(Cl)cc(cc1Cl)N1CC2CC1CO2

InChI Key InChIKey=NDJADBPAAPJNEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 672851   

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672851(US20240150287, Example 20 | (2S)-2-(4-(2-oxa-5-aza...)
Affinity DataIC50: 4.15nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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