BDBM672840 (S)-3-(4-(6′-chloro-5′-fluoro-2′-oxospiro[cyclopropane-1,3′-indoline]-1′-yl)phenyl)-2-(triphenylamino)methyl propionate::US20240150287, Example 8

SMILES COC(=O)[C@H](Cc1ccc(cc1)N1C(=O)C2(CC2)c2cc(F)c(Cl)cc12)NC(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=JXVJCKNLRCASNC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 672840   

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672840(US20240150287, Example 8 | (S)-3-(4-(6′-chlo...)
Affinity DataIC50: 17.6nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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