BDBM672839 (S)-3-(4-(7-chloro-2-oxo-2′,3′,5′,6′-tetrahydrospiro[indoline-3,4′-pyran]-1-yl)phenyl)-2-(triphenylamino)methyl propionate::US20240150287, Example 7

SMILES COC(=O)[C@H](Cc1ccc(cc1)N1C(=O)C2(CCOCC2)c2cccc(Cl)c12)NC(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=WGVKDHVFQFYJGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 672839   

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672839(US20240150287, Example 7 | (S)-3-(4-(7-chloro-2-ox...)
Affinity DataIC50: 16.1nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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