BDBM669886 2-{[6- (hydroxymethyl)pyridin-2- yl]carbamoyl}-5- (trifluoromethyl)benzoic acid::US20240132514, Example 3

SMILES OCc1cccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1

InChI Key InChIKey=YWJABRMYLFXHKU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669886   

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669886(US20240132514, Example 3 | 2-{[6- (hydroxymethyl)p...)
Affinity DataIC50: 340nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669886(US20240132514, Example 3 | 2-{[6- (hydroxymethyl)p...)
Affinity DataKi:  340nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent