BDBM669885 2-({5H,6H,8H-pyrano[3,4- b]pyridin-2-yl}carbamoyl)-5- (trifluoromethyl)benzoic acid::US20240132514, Example 2

SMILES OC(=O)c1cc(ccc1C(=O)Nc1ccc2CCOCc2n1)C(F)(F)F

InChI Key InChIKey=NILRIZWEOLEABR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669885   

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669885(US20240132514, Example 2 | 2-({5H,6H,8H-pyrano[3,4...)
Affinity DataIC50: 60nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetSortilin(Human)
Insusense

US Patent
LigandPNGBDBM669885(US20240132514, Example 2 | 2-({5H,6H,8H-pyrano[3,4...)
Affinity DataIC50: 105nMAssay Description:The compound affinity was determined by measuring the inhibition of 3H-neurotensin and/or 125I-neurotensin binding to human full length sortilin usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent