BDBM669213 US11964973, Example 200

SMILES CC(C)Oc1ccc(O[C@@H]2CCN(CC2C)c2cc(=O)n(C)c3ccc(nc23)C#N)nc1

InChI Key InChIKey=QVQWJILQVOREAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669213   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM669213(US11964973, Example 200)
Affinity DataIC50: 39nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays). The reactions were carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM669213(US11964973, Example 200)
Affinity DataIC50: 1.60E+3nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays). The reactions were carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent