BDBM667986 (2R,3R,4S,5R,6R)-N-(3-bromo-5-methylphenyl)-5-hydroxy-6- (hydroxymethyl)-N-((3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl)-3- methoxy-4-(4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H- pyran-2-carboxamide::US20240124427, Example 102

SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(F)c(F)c1)C(=O)N([C@H]1CCOC[C@@H]1O)c1cc(C)cc(Br)c1

InChI Key InChIKey=KARZLHOIXKEUBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 667986   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM667986(US20240124427, Example 102 | (2R,3R,4S,5R,6R)-N-(3...)
Affinity DataIC50: 14nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM667986(US20240124427, Example 102 | (2R,3R,4S,5R,6R)-N-(3...)
Affinity DataIC50: 311nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent