BDBM667897 (2R,3R,4S,5R,6R)-4-(4-(4-bromo-2,3-difluorophenyl)-1H-1,2,3-triazol-1- yl)-N-(3-bromo-5-cyanophenyl)-5-hydroxy-6-(hydroxymethyl)-N- ((3S,4R)-4-hydroxytetrahydrofuran-3-yl)-3-methoxytetrahydro-2H- pyran-2-carboxamide::US20240124427, Example 13

SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Br)c(F)c1F)C(=O)N([C@H]1COC[C@@H]1O)c1cc(Br)cc(c1)C#N

InChI Key InChIKey=KGJVRVDBCVQQKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 667897   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM667897(US20240124427, Example 13 | (2R,3R,4S,5R,6R)-4-(4-...)
Affinity DataIC50: 15nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM667897(US20240124427, Example 13 | (2R,3R,4S,5R,6R)-4-(4-...)
Affinity DataIC50: 593nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent