BDBM667091 3-(4-{2-[bis(2- hydroxyethyl)amino]ethyl}piperazin- 1-yl)-N-{4-[7-(5-chloro-2- fluorophenyl)-1H,2H,3H- pyrido[3,4-b][1,4]oxazin-1- yl]pyridin-2-yl}propanamide::US20240116947, Example 36

SMILES OCCN(CCO)CCN1CCN(CCC(=O)Nc2cc(ccn2)N2CCOc3cnc(cc23)-c2cc(Cl)ccc2F)CC1

InChI Key InChIKey=QQXKFZMPONLUQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667091   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667091(US20240116947, Example 36 | 3-(4-{2-[bis(2- hydrox...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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