BDBM667077 3-[bis(oxetan-3-yl)amino]-N-{4-[7- (5-chloro-2- fluorophenyl)-1H,2H,3H- pyrido[3,4-b][1,4]oxazin-1- yl]pyridin-2-yl}propanamide::US20240116947, Example 21

SMILES Fc1ccc(Cl)cc1-c1cc2N(CCOc2cn1)c1ccnc(NC(=O)CCN(C2COC2)C2COC2)c1

InChI Key InChIKey=XOAPUFXAXLDDSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667077   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667077(US20240116947, Example 21 | 3-[bis(oxetan-3-yl)ami...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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