BDBM665688 6-(4-((1R,3R,5S)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)phenyl)-1,2,4-triazine-3,5(2H,4H)-dione::US20240116912, Example 67

SMILES FC(F)(F)Oc1ccccc1-c1noc(C2CC2)c1CO[C@@H]1C[C@@H]2CC[C@H](C1)N2c1ccc(cc1)-c1n[nH]c(=O)[nH]c1=O

InChI Key InChIKey=OAGWWMMZMMPWBJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665688   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM665688(US20240116912, Example 67 | 6-(4-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  12.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
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US Patent