BDBM664725 US20240116877, Example 43::US20240116877, Example 9

SMILES COCCOc1cc(F)c2c(Nc3ccc(NC(=O)NCCC(C)(C)C)cc3)ncnc2c1

InChI Key InChIKey=KQAKOSTUYOYZGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 664725   

TargetMast/stem cell growth factor receptor Kit [544-976](Human)
Deciphera Pharmaceuticals, LLC

US Patent
LigandPNGBDBM664725(US20240116877, Example 43 | US20240116877, Example...)
Affinity DataIC50: 10nMAssay Description:Activity of c-KIT kinase (SEQ. ID NO. 1 or SEQ. ID NO. 2) was determined spectroscopically using a coupled pyruvate kinase/lactate dehydrogenase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit [544-976](Human)
Deciphera Pharmaceuticals, LLC

US Patent
LigandPNGBDBM664725(US20240116877, Example 43 | US20240116877, Example...)
Affinity DataIC50: 55nMAssay Description:Activity of c-KIT kinase (SEQ. ID NO. 1 or SEQ. ID NO. 2) was determined spectroscopically using a coupled pyruvate kinase/lactate dehydrogenase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent