BDBM663912 US20240109915, Example 97

SMILES CNc1nc2c(C)cccc2cc1C(=O)N1CCC2(CC1)Cc1sc(nc1C(=O)C2)C(C)(C)C

InChI Key InChIKey=CPJGGABKNIYFOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 663912   

TargetAcetyl-CoA carboxylase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM663912(US20240109915, Example 97)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full length human recombinant ACC1 expressed in baculovirus infected Sf9 cells incubated for 18 hrs in presence of ATP by envision fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
LigandPNGBDBM663912(US20240109915, Example 97)
Affinity DataIC50: 1.80nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent