BDBM663858 US20240109915, Example 40

SMILES CNc1ccc2c(OC)cc(cc2n1)C(=O)N1CCC2(CC1)Cc1sc(nc1C(=O)C2)C(C)(C)C

InChI Key InChIKey=KSNSQBRZIXKYRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 663858   

TargetAcetyl-CoA carboxylase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM663858(US20240109915, Example 40)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length human recombinant ACC1 expressed in baculovirus infected Sf9 cells incubated for 18 hrs in presence of ATP by envision fluo...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM663858(US20240109915, Example 40)
Affinity DataIC50: 1.5nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
In DepthDetails
US Patent