BDBM66357 4-Cyano-5-[2-(3-cyano-4,6-dimethyl-pyridin-2-ylsulfanyl)-acetylamino]-3-methyl-thiophene-2-carboxylic acid ethyl ester::4-cyano-5-[[2-[(3-cyano-4,6-dimethyl-2-pyridinyl)thio]-1-oxoethyl]amino]-3-methyl-2-thiophenecarboxylic acid ethyl ester::4-cyano-5-[[2-[(3-cyano-4,6-dimethyl-2-pyridyl)thio]acetyl]amino]-3-methyl-thiophene-2-carboxylic acid ethyl ester::MLS000555968::SMR000147485::cid_1772736::ethyl 4-cyano-5-[2-(3-cyano-4,6-dimethyl-pyridin-2-yl)sulfanylethanoylamino]-3-methyl-thiophene-2-carboxylate::ethyl 4-cyano-5-[[2-(3-cyano-4,6-dimethylpyridin-2-yl)sulfanylacetyl]amino]-3-methylthiophene-2-carboxylate

SMILES CCOC(=O)c1sc(NC(=O)CSc2nc(C)cc(C)c2C#N)c(C#N)c1C

InChI Key InChIKey=JAEKHQRRETWEMY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 66357   

TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66357(MLS000555968 | ethyl 4-cyano-5-[2-(3-cyano-4,6-dim...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay