BDBM663048 US20240109890, Compound 2

SMILES Cn1cc(Nc2nccc(n2)C2=CC3CCC(C2)N3C(=O)[C@H]2C[C@@H]2F)cn1

InChI Key InChIKey=ISSYANIZZYOSCZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663048   

TargetTyrosine-protein kinase JAK1(Human)
The National Institutes Of Pharmaceutical R&D Co.

US Patent
LigandPNGBDBM663048(US20240109890, Compound 2)
Affinity DataIC50: 650nMAssay Description:Experimental materials: JAK1 kinase (Invitrogen, PV4744), ATP (Promega, V915B), ADP-Glo Kinase Assay (Promega, V9101), IRS1 (Signalchem, 140-58-1000)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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