BDBM663038 Synthesis of 2-methoxy-N-(6-(thiazol-2-yloxy)-2,3,4,5,9,10-hexahydrooxepino[3′,2′:5,6]benzo[1,2-d]isoxazol-10-yl)benzenesulfonamide ::US20240109880, Compound 63

SMILES COc1ccccc1S(=O)(=O)Nc1noc2cc(Oc3nccs3)c3CCCCOc3c12

InChI Key InChIKey=NHRGUMRLZQGCFR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663038   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM663038(Synthesis of 2-methoxy-N-(6-(thiazol-2-yloxy)-2,3,...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KAT6A enzymatic activity by test compounds was determined using a radiometric 384-well format assay. A 10-point serial dilution of the ...More data for this Ligand-Target Pair
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Date in BDB:
6/20/2024
Entry Details
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