BDBM662971 US20240109879, Compound 7B

SMILES COC12CCC(CC1)(CC2)n1c(nc2cc(ccc12)-c1c(C)noc1C)[C@H]1CCCC(=O)N1c1ccc(F)c(F)c1

InChI Key InChIKey=DGOLCOFYVOLBRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 662971   

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandPNGBDBM662971(US20240109879, Compound 7B)
Affinity DataIC50: 4.11nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent