BDBM662966 US20240109879, Compound 2B

SMILES Cc1noc(C)c1-c1ccc2n(C3CC4C(C3)C4(F)F)c(nc2c1)[C@H]1CCCC(=O)N1c1ccc(F)c(F)c1

InChI Key InChIKey=OISTZKLYQBJTIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662966   

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandPNGBDBM662966(US20240109879, Compound 2B)
Affinity DataIC50: 3.54nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCREB-binding protein(Human)
Medshine Discovery

US Patent
LigandPNGBDBM662966(US20240109879, Compound 2B)
Affinity DataIC50: 0.670nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent