BDBM662944 5-[5-[(1R)-1-(3,5-dichloro-4- pyridyl)ethoxy]-6-fluoro-1H- indazol-3-yl]-2-(6,6-dioxo-6lambda6- thia-2-azaspiro[3.4]octan-2- yl)pyridine-3-carbonitrile::US20240109865, Example 378.

SMILES C[C@@H](Oc1cc2c(n[nH]c2cc1F)-c1cnc(N2CC3(C2)CCS(=O)C3)c(c1)C#N)c1c(Cl)cncc1Cl

InChI Key InChIKey=AWBYPEWMPJFEMQ-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 662944   

TargetFibroblast growth factor receptor 1(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662944(US20240109865, Example 378. | 5-[5-[(1R)-1-(3,5-di...)
Affinity DataKd:  200nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662944(US20240109865, Example 378. | 5-[5-[(1R)-1-(3,5-di...)
Affinity DataKd:  60nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662944(US20240109865, Example 378. | 5-[5-[(1R)-1-(3,5-di...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3 [V555M](Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662944(US20240109865, Example 378. | 5-[5-[(1R)-1-(3,5-di...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 4(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662944(US20240109865, Example 378. | 5-[5-[(1R)-1-(3,5-di...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In DepthDetails
US Patent