BDBM661140 6-methoxy-3-(4-methoxypyridin-3-yl)- 2-[4-(4-methyl-4H-1,2,4-triazol-3- yl)piperidin-1-yl]benzonitrile::US20240101544, Example 25

SMILES COc1ccncc1-c1ccc(OC)c(C#N)c1N1CCC(CC1)c1nncn1C

InChI Key InChIKey=FXVADSWSDMAPDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661140   

LigandPNGBDBM661140(US20240101544, Example 25 | 6-methoxy-3-(4-methoxy...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661140(US20240101544, Example 25 | 6-methoxy-3-(4-methoxy...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent