BDBM661123 3-{4-[2- (dimethylamino)ethoxy]pyridin-3-yl}- 2-[4-(4-methyl-4H-1,2,4-triazol-3- yl)piperidin-1-yl]benzonitrile::US20240101544, Example 8

SMILES CN(C)CCOc1ccncc1-c1cccc(C#N)c1N1CCC(CC1)c1nncn1C

InChI Key InChIKey=YFAOKEBBZLQNMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661123   

LigandPNGBDBM661123(US20240101544, Example 8 | 3-{4-[2- (dimethylamino...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2024
Entry Details
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TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661123(US20240101544, Example 8 | 3-{4-[2- (dimethylamino...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent