BDBM661121 3-[6-(2-hydroxyethoxy)pyridin-3-yl]-2- [4-(4-methyl-4H-1,2,4-triazol-3- yl)piperidin-1-yl]benzonitrile::US20240101544, Example 6

SMILES Cn1cnnc1C1CCN(CC1)c1c(cccc1-c1ccc(OCCO)nc1)C#N

InChI Key InChIKey=WVZTYAOBXYXFSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661121   

LigandPNGBDBM661121(US20240101544, Example 6 | 3-[6-(2-hydroxyethoxy)p...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661121(US20240101544, Example 6 | 3-[6-(2-hydroxyethoxy)p...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent