BDBM661115 US20240101551, Compound of Formula I

SMILES Cn1cc(-c2nc(CS(C)(=O)=O)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O

InChI Key InChIKey=YXUDVCOHGOVDDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661115   

TargetBromodomain-containing protein 4 [75-147](Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM661115(US20240101551, Compound of Formula I)
Affinity DataIC50: 0.640nMAssay Description:In the present application, the IC50 value of the compound of formula (I) in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogen...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 4 [368-440](Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM661115(US20240101551, Compound of Formula I)
Affinity DataIC50: 0.25nMAssay Description:In the present application, the IC50 value of the compound of formula (I) in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogen...More data for this Ligand-Target Pair
In DepthDetails
US Patent