BDBM659784 N6-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-N3-((tetrahydro-2H-pyran-4-yl)methyl)-4,5-dihydropyrazolo[1,5-a]pyrimidine-3,6-dicarboxamide::US20240092784, Example 221

SMILES CC(C)Cn1c2c(cnn2c(O)c(C(=O)NC2CC2)c1=O)C(=O)NCC1CCOCC1

InChI Key InChIKey=ROTWQTZLWPWUDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659784   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM659784(N6-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-N3-((tet...)
Affinity DataIC50: 0.640nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In DepthDetails
US Patent