BDBM656590 N-ethyl-2-((4-(7-(((2S,5R)-5- (ethylsulfonamido)tetrahydro-2H-pyran-2- yl)methyl)-2,7-diazaspiro[3.5]nonan-2- yl)pyrimidin-5-yl)oxy)-5-fluoro-N- isopropylbenzamide::US11919901, Compound 2::US11919901, Compound 52

SMILES CCN(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@@H]1CC[C@H](CO1)NS(=O)(=O)CC)CC2

InChI Key InChIKey=MYHKPCHFHONPJC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 656590   

TargetMenin(Human)
Syndax Pharmaceuticals

US Patent
LigandPNGBDBM656590(N-ethyl-2-((4-(7-(((2S,5R)-5- (ethylsulfonamido)te...)
Affinity DataIC50: 100nMAssay Description:For IC50 determination test compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system. Lower sub-sto...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMenin(Human)
Syndax Pharmaceuticals

US Patent
LigandPNGBDBM656590(N-ethyl-2-((4-(7-(((2S,5R)-5- (ethylsulfonamido)te...)
Affinity DataIC50: 100nMAssay Description:For IC50 determination test compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system. Lower sub-sto...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Syndax Pharmaceuticals

US Patent
LigandPNGBDBM656590(N-ethyl-2-((4-(7-(((2S,5R)-5- (ethylsulfonamido)te...)
Affinity DataKi: <1nMAssay Description:Table 4: For Ki determination, individual compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system....More data for this Ligand-Target Pair
In DepthDetails
US Patent