BDBM656562 US11919887, Compound 94

SMILES COc1c(F)c(F)ccc1[C@@H]1[C@H](O[C@@](C)([C@@H]1C1CC1)C(F)(F)F)C(=O)Nc1ccnc(c1)C(N)=O

InChI Key InChIKey=ADJYUTDHUPEPHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656562   

TargetSodium channel protein type 5 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM656562(US11919887, Compound 94)
Affinity DataIC50: 10nMAssay Description:Assay Protocol (7 Key Steps):1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
Go to US Patent