BDBM656542 US11919887, Compound 74::rel-(2R,3S,5R)-4-[[3-[2-

SMILES C[C@@]1(C[C@H]([C@@H](O1)C(=O)Nc1ccnc(c1)C(N)=O)c1ccc(F)cc1OC(F)F)C(F)(F)F

InChI Key InChIKey=YDZBSQORRYRCTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656542   

TargetSodium channel protein type 5 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM656542(US11919887, Compound 74 | rel-(2R,3S,5R)-4-[[3-[2-)
Affinity DataIC50: 55nMAssay Description:Assay Protocol (7 Key Steps):1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
Go to US Patent