BDBM65516 CHEBI:84382::CHEMBL2426321::Chondramide C

SMILES C[C@H]1OC(=O)C[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)N(C)C(=O)[C@H](C)NC(=O)[C@@H](C)C\C(C)=C\[C@H]1C)c1ccc(O)cc1

InChI Key InChIKey=NCRSWJPOFRASIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 65516   

TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.67E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.19E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.51E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed