BDBM653656 US11911372, Example 78::US20240277683, Example 78

SMILES Cc1ccc(cc1C)S(=O)(=O)Nc1cc(no1)-c1cccc(CCc2ccccc2)c1

InChI Key InChIKey=IIQWHJRMGWBZAS-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 653656   

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 1.30E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 1.08E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 768nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 2.51E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 768nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 2.51E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 1.30E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653656(US11911372, Example 78 | US20240277683, Example 78)
Affinity DataIC50: 1.08E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent