BDBM653591 US11911372, Example 12::US20240277683, Example 12

SMILES CCc1ccc(OC)c(c1)S(=O)(=O)Nc1cc(on1)-c1ccc(OC)cc1OC

InChI Key InChIKey=INDAFGAAIMGEAV-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 653591   

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 4.47E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 1.03E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 3.10E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 615nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 1.03E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 3.10E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 615nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653591(US11911372, Example 12 | US20240277683, Example 12)
Affinity DataIC50: 4.47E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In DepthDetails
US Patent