BDBM653559 7′-(2,6-dioxopiperidin-3-yl)-7′-hydro-3′H,6′H-spiro[azetidine-3,2′-[1,4]dioxino[2,3-f]isoindole]-6′,8′-dione::US20240059704, Compound B5

SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)c2cc3OC4(CNC4)COc3cc12

InChI Key InChIKey=QMZNGUCUZXIOPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653559   

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653559(US20240059704, Compound B5 | 7′-(2,6-dioxopi...)
Affinity DataIC50: 4.63E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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