BDBM653558 (S)-3-(6′-oxo-6′,8′-dihydro-3′H,7′H-spiro[azetidine-3,2′-[1,4]dioxino[2,3-f]isoindol]-7′-yl)piperidine-2,6-dione::US20240059704, Compound B4

SMILES O=C1N(Cc2cc3OC4(CNC4)COc3cc12)[C@H]1CCC(=O)NC1=O

InChI Key InChIKey=UTWMARIFAWDFMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653558   

TargetProtein cereblon(Human)
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US Patent
LigandPNGBDBM653558(US20240059704, Compound B4 | (S)-3-(6′-oxo-6...)
Affinity DataIC50: 4.33E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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