BDBM653551 3-(7'-oxo-7',9'-dihydro-8'H- spiro[piperidine-4,2'- pyrano[2,3-e]isoindol]-8'- yl)piperidine-2,6-dione::US20240059704, Compound A1

SMILES O=C1N(Cc2c1ccc1C=CC3(CCNCC3)Oc21)C1CCC(=O)NC1=O

InChI Key InChIKey=PUFDUXUYQPVSEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653551   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
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US Patent
LigandPNGBDBM653551(US20240059704, Compound A1 | 3-(7'-oxo-7',9'-dihyd...)
Affinity DataIC50: 1.10E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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