BDBM653019 (M)-1-(6- ((1S,8R)-5- methyl-6-(1,5,6- trimethyl-1H- indazol-7-yl)-3- azatricyclo [6.2.1.02,7]undeca- 2,4,6-trien-4-yl)- 2,6- diazaspiro[3.4] octan-2-yl)-2- propen-1-one (2nd eluting isomer)::US20240059703, Example 2-111

SMILES Cc1cc2cnn(C)c2c(c1C)-c1c2[C@@H]3CC[C@@H](C3)c2nc(N2CCC3(CN(C3)C(=O)C=C)C2)c1C

InChI Key InChIKey=KRTREUCSQZZXGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653019   

LigandPNGBDBM653019(US20240059703, Example 2-111 | (M)-1-(6- ((1S,8R)-...)
Affinity DataIC50: 3nMAssay Description:Purified GDP-bound KRAS protein (aa 1-169), containing both G12C and C118A amino acid substitutions and an N-terminal His-tag, was pre-incubated in a...More data for this Ligand-Target Pair
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US Patent