BDBM652690 4-chloro-6-N-{[2-({2-methyl-5H,6H,7H,8H-imidazo[1,2-a]pyridin-7-yl}methoxy)pyridin-4- yl]methyl}isoquinoline-1,6-diamine::US20240059691, Example 4309
SMILES Cc1cn2CCC(COc3cc(CNc4ccc5c(N)ncc(Cl)c5c4)ccn3)Cc2n1
InChI Key InChIKey=CSNSELBEUILYAV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 652690
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair