BDBM651449 (S)-1-(3-(4-(2-(2-Chlorophenyl)-3-(hydroxymethyl)imidazo[2,1-f][1,6]naphthyridin-9-yl)-1H-pyrazol-1-yl)pyrrolidin-1-yl)ethan-1-one::US11897891, Example 64

SMILES CC(=O)N1CC[C@@H](C1)n1cc(cn1)-c1cnc2ccn3c(CO)c(nc3c2c1)-c1ccccc1Cl

InChI Key InChIKey=WWQXFTQVSXBBFR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651449   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM651449(US11897891, Example 64 | (S)-1-(3-(4-(2-(2-Chlorop...)
Affinity DataKi: <10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
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Date in BDB:
4/18/2024
Entry Details
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