BDBM65076 (4,5-dichloro-6-oxopyridazin-1-yl)methyl 3-(trifluoromethyl)benzoate::3-(trifluoromethyl)benzoic acid (4,5-dichloro-6-keto-pyridazin-1-yl)methyl ester::3-(trifluoromethyl)benzoic acid (4,5-dichloro-6-oxo-1-pyridazinyl)methyl ester::MLS000546964::SMR000180162::[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]methyl 3-(trifluoromethyl)benzoate::[4,5-dichloro-6-oxo-1(6H)-pyridazinyl]methyl 3-(trifluoromethyl)benzenecarboxylate::cid_1474463

SMILES FC(F)(F)c1cccc(c1)C(=O)OCn1ncc(Cl)c(Cl)c1=O

InChI Key InChIKey=VIJKPGLSWADBGL-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 65076   

TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM65076(3-(trifluoromethyl)benzoic acid (4,5-dichloro-6-ox...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM65076(3-(trifluoromethyl)benzoic acid (4,5-dichloro-6-ox...)
Affinity DataIC50: 4.40E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM65076(3-(trifluoromethyl)benzoic acid (4,5-dichloro-6-ox...)
Affinity DataIC50: 4.49E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM65076(3-(trifluoromethyl)benzoic acid (4,5-dichloro-6-ox...)
Affinity DataIC50: 5.69E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM65076(3-(trifluoromethyl)benzoic acid (4,5-dichloro-6-ox...)
Affinity DataIC50: 4.40E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay