BDBM649748 (3-fluoro-4-hydroxy-5- ((morpholinoimino)methyl) phenyl)(4-(4-(pyrrolidin-1- yl)phenyl)piperidin-1- yl)methanone::US20240043395, Compound 164

SMILES Oc1c(F)cc(cc1\C=N\N1CCOCC1)C(=O)N1CCC(CC1)c1ccc(cc1)N1CCCC1

InChI Key InChIKey=WMQSENFFMAIIAO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 649748   

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649748((3-fluoro-4-hydroxy-5- ((morpholinoimino)methyl) p...)
Affinity DataIC50: 1.10E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649748((3-fluoro-4-hydroxy-5- ((morpholinoimino)methyl) p...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 9(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649748((3-fluoro-4-hydroxy-5- ((morpholinoimino)methyl) p...)
Affinity DataIC50: 260nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent