BDBM649499 US11891386, Compound ARI-118

SMILES Nc1nnc(o1)-c1csc(n1)C(=O)c1c[nH]c2c(F)cccc12

InChI Key InChIKey=NMJJTYCWVGBYNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649499   

TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649499(US11891386, Compound ARI-118)
Affinity DataIC50: 0.800nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In DepthDetails
US Patent